Work

Synthesis and Biological Activity of Some Novel Phenyl Pyrazoline Derivatives

Year: 2012
Type: article
Abstract: A new series of 4-(4-hydroxyphenyl)-3-chloro-1-{4-[5-(substituted phenyl)-1-phenyl-4,5dihydro-pyrazol-3-yl]phenyl}azetidin-2-one were synthesized by reacting 3-chloro-1-{4-[3-(substituted-phenyl)prop-2-enoyl]phenyl}-4-(4-hydroxyphenyl)azetidin-2-one (0.01 M) and phenyl hydrazine (0.01 M) in presence of acetic acid (glacial).All these compounds were characterized by means of their IR, 1 H NMR, spectroscopic data and microanalysis.All the synthesized products were evaluated for their antimicrobial activity.All the compounds were tested for their antibacterial and antifungal activities by broth dilution method.
Language: English
Field: Chemistry
Open Access status: bronze
OpenAlex ID: W1998559196
FWCI: 0.41
Cites: 5
Cited by: 18
Related to: 10