Work

Bipolar cellular morphology of malignant melanoma in unstained human melanoma skin tissue

Year: 2009

Type: article

Abstract: Microstructures of unstained human melanoma skin tissues have been examined by multimodal nonlinear optical microscopy. The polarized shape of the individual melanoma cell can be readily recognized-a phenotype that has been identified in laboratory cultures as characteristic of proliferating melanocytes but has not been demonstrated in clinical instances. The results thus provide snapshots of invading melanoma cells in their native environment and suggest a practical means of connecting in vitro laboratory studies to in vivo processes.

Source: Journal of Biomedical Optics

DOI: 10.1117/1.3120491

Authors: Kai Zhang, Wenkai Zhang, Chia-Yi Yang, Haw Yang

Institutions: University of California, Berkeley, Taipei Municipal YangMing Hospital, Taipei City Hospital

Language: English

Topic: Cutaneous Melanoma Detection and Management

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Science Foundation, U.S. Department of Energy, Alfred P. Sloan Foundation, University of California Berkeley