Work

Antifungal Activity of Coumarins

Year: 2008

Type: article

Abstract: The antifungal activity of 40 coumarins was tested against the fungal strains: Candida albicans (ATCC 14053), Aspergillus fumigatus (ATCC 16913) and Fusarium solani (ATCC 36031), using the broth microdilution method. Osthenol showed the most effective antifungal activity among all the compounds tested, with a MIC value of 125 microg/ml for Fusarium solani and 250 micro/ml for Candida albicans and Aspergillus fumigatus. The antifungal potential of this prenylated coumarin can be related to the presence of an alkyl group at C-8 position.

Source: Zeitschrift für Naturforschung C

DOI: 10.1515/znc-2008-1-205

Authors: Cristina Montagner, Simone M. de Souza, Cláudia Groposo, Franco Delle Monache, Elza F. A. Smânia, Artur Smânia Jr

Institutions: Universidade Federal de Santa Catarina, Università Cattolica del Sacro Cuore

Language: English

Topic: Plant chemical constituents analysis

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $2,712

OpenAlex ID: W2000400913

FWCI: 2.418

Cites: 24

Cited by: 121

Related to: 10