Work

Gout with auricular tophi following anti-tuberculosis treatment: a case report

Year: 2013
Type: article
Study design: Case Report
Abstract: BACKGROUND: Auricular tophi are firm deposits of monosodium urate in crystal form, which may slowly develop in subcutaneous tissue of the ear. Ear is not usual locations for gout tophi, but when this growth does occur, helix and the antihelix are common sites. CASE PRESENTATION: We present a 64-year-old man who had multiple painless nodules over bilateral helix. An excisional biopsy was performed. Hematoxylin-eosin staining of biopsy specimens revealed a proteinaceous matrix that surrounded dissolved crystals, consistent with gout tophi. Bilateral auricular tophi are not common and may resemble a number of other diseases including squamous cell carcinomas, Kaposi's sarcoma, epidermal and dermoid cysts, rheumatoid nodules. Biopsy should be performed to rule out malignancy. CONCLUSIONS: Tophi of the auricle are usually asymptomatic but can become inflamed and occasionally ulcerate through the overlying skin. Chronic tophaceous gout is treated with dietary control and medication. Surgical excision is performed under local anesthetic if symptoms progression or cosmetically deformity is concerned.
Language: English
Subfield: Nephrology
Field: Medicine
Open Access status: gold
Estimated APC paid: $1,690
OpenAlex ID: W2000536683
FWCI: 0.229
Cites: 5
Cited by: 8
Related to: 9