Work

Germacranolides and a New Type of Guaianolide from Acanthospermum hispidum

Year: 2000

Type: article

Abstract: The aerial parts of an Argentinian collection of Acanthospermum hispidum afforded 26 sesquiterpene lactones, including the two guaianolides (1 and 2) having a novel oxygen bridge between C-4 and C-14, three new cis,cis-germacranolides (4, 7, and 8), and two new melampolides (25 and 26). Guaianolides 1 and 2 seem to derive biosynthetically from the germacranolide 27 having the (1)D(14, 15)D(5) conformation. The structures were elucidated using extensive spectroscopic analysis.

Source: Journal of Natural Products

DOI: 10.1021/np9905057

Authors: Elena Cartagena, Alicia Bardón, César A. N. Catalán, Zaida N. J. de Hernández, Luis R. Hernández, Pedro Joseph-Nathan

Institutions: National University of Tucumán, Instituto Politécnico Nacional, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional

Language: English

Topic: Sesquiterpenes and Asteraceae Studies

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: Consejo Nacional de Investigaciones Científicas y Técnicas, CYTED Ciencia y Tecnología para el Desarrollo, Agencia Nacional de Promoción Científica y Tecnológica

Award: G7378882120