Clinical Features of Acute Retroviral Syndrome Differ by Route of Infection but Not by Gender and Age
Year: 2002
Type: article
Abstract: The rate of HIV disease progression is associated with the severity of the acute retroviral syndrome (ARS). We explored the clinical features of ARS by gender, age and route of infection among 378 individuals with documented ARS enrolled in 5 prospective cohort studies with similar enrollment criteria. No major differences were detected by gender or by age. Several symptoms were reported less frequently in the injecting drug users as compared with infection acquired through sexual contacts (either heterosexual or homosexual). This was observed in particular for fever (50% vs. 77%, p=.001), skin rash (21% vs. 51%, p=.001), pharyngitis (18% vs. 43%, p=.004), and myalgia (29% vs. 52%, p=.01). Genital ulcerations were present only in cases of sexual exposure to HIV. Injecting drug users had or reported symptoms associated with the ARS less frequently than persons acquiring HIV via sexual transmission.
Institutions: Lyon 1 Université, Inserm, University of Washington, McGill University Health Centre, UNSW Sydney, St Vincent's Hospital Sydney, University Hospital of Geneva, Hôpital Edouard Herriot, Hôtel-Dieu de Lyon, Mark Wainberg Centre for Viral Diseases, McGill University, Université de Montréal
Language: English
Topic: HIV Research and Treatment
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2000911003