Work

Comparative study of different species of oxygen free radicals on the ATP-sensitive potassium channels of the heart

Year: 1994

Type: article

Abstract: The effects of vasoactive intestinal polypeptide (VIP) on catecholamine (CA) secretion by isolated guinea pig adrenal medullary cells were studied. VIP (1 μM) alone induced only a slight secretion of CA, but it stimulated ACh-induced CA secretion. At concentrations of 0.01–1 μM, it stimulated muscarine-induced CA secretion, but not nicotine-induced CA secretion. It did not affect high K+ or Ca2+ ionophore-induced CA secretion. The stimulatory effect of VIP on muscarine-induced CA secretion was observed at muscarine concentrations of 2–200 μM and was detectable after 2 min incubation.

Source: Pathophysiology

DOI: 10.1016/0928-4680(94)90960-1

Authors: K. Tokube, T. Kiyosue, M. Arita

Language: English

Topic: Neuropeptides and Animal Physiology

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,689

OpenAlex ID: W2003159154

FWCI:

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Related to: 10