Clinical characteristics of human infection with a novel avian-origin influenza A(H10N8) virus
Year: 2014
Type: article
Study design: Case Report
Abstract: BACKGROUND: Novel influenza A viruses of avian-origin may be the precursors of pandemic strains. This descriptive study aims to introduce a novel avian-origin influenza A (H10N8) virus which can infect humans and cause severe diseases. METHODS: Collecting clinical data of three cases of human infection with a novel reassortment avian influenza A (H10N8) virus in Nanchang, Jiangxi Province, China. RESULTS: Three cases of human infection with a new reassortment avian influenza A(H10N8) virus were described, of which two were fatal cases, and one was severe case. These cases presented with severe pneumonia that progressed to acute respiratory distress syndrome (ARDS) and intractable respiratory failure. CONCLUSION: This novel reassortment avian influenza A (H10N8) virus in China resulted in fatal human infections, and should be added to concerns in clinical practice.
Source: Chinese Medical Journal
Authors: Zhang Wei, Wan Jianguo, Qian Kejian, Liu Xiaoqing, Xiao Zuke, Sun Jian, Zeng Zhenguo, Wang Qi, Zhang Jinxiang, Jiang Guanghui, Nie Cheng, Jiang Rong, Ding Chengzhi, Li Ran, Horby Peter, Gao Zhancheng
Institutions: Nanchang University, Chinese Center For Disease Control and Prevention, Jiangxi Provincial People's Hospital, Peking University People's Hospital, Oxford University Clinical Research Unit, Nanchang Center for Disease Control and Prevention, First Affiliated Hospital of Nanchang University, Wellcome Trust
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,000
OpenAlex ID: W200323671