Work

Estimation of Duration of Symptoms in Fulminant Type 1 Diabetes Mellitus Using HbA1c or Glycated Albumin

Year: 2012

Type: article

Abstract: Fulminant type 1 diabetes mellitus (FT1DM) develops as a result of very rapid and almost complete destruction of pancreatic β cells. Because of an abrupt increase in plasma glucose, HbA1c and glycated albumin (GA) might increase along with duration of symptoms in FT1DM patients. We attempted to devise a formula to estimate duration of symptoms based on the increased levels in HbA1c or GA. Four patients who developed FT1DM during the course of type 2 diabetes mellitus and in whom HbA1c was measured before onset were investigated in this study. The percents of the estimated duration of symptoms calculated from HbA1c (four patients) and GA (two patients) to the actual duration were 137 ± 88% and 122%, respectively. In FT1DM patients in whom HbA1c and/or GA before onset and at the time of ketoacidosis are measured, duration of symptoms might be estimated with using the increased levels in HbA1c or GA.

Source: Japanese Clinical Medicine

DOI: 10.4137/jcm.s9509

Authors: Akitsu Kawabe, Takashi Seta, Sumie Fujii, Masayo Yamada, Shogo Oki, Jun Murai, Hiroshi Saito, Masafumi Koga

Institutions: Ishikawa Prefectural Central Hospital, Yokohama Sakae Kyosai Hospital, Osaka Red Cross Hospital, Kinki Central Hospital

Language: English

Topic: Diabetes Management and Research

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W2005361943

FWCI:

Cites: 19

Cited by:

Related to: 10