Work

Neutralization of murine myeloid-derived suppressor cells enhances the efficacy of a chimeric antigen receptor T-cells directed against pediatric solid tumors

Year: 2013

Type: article

Abstract: Meeting abstracts Genetically engineered T-cells that express chimeric antigen receptors (CARs) to directly target tumor-expressed antigens have shown remarkable activity in clinical trials for hematologic malignancies, but remain unproven for the treatment of solid tumors. We find that in addition

Source: Journal for ImmunoTherapy of Cancer

DOI: 10.1186/2051-1426-1-s1-p265

Authors: Steven L Highfill, Adrienne H Long, Rimas J Orentas, Crystal L Mackall

Institution: National Cancer Institute

Language: English

Topic: CAR-T cell therapy research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,490