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NEURONAL TUMOR CELLS WITH EXCITABLE MEMBRANES GROWN in vitro

Year: 1969

Type: article

Abstract: Mouse neuroblastoma cells grown in vitro are capable of generating action potentials in response to electrical stimulation. A wide spectrum of responses was observed with different cells ranging from passive responses to action potentials. A hypothesis is proposed concerning the acquisition of electrical excitability as neuroblasts mature into neurons.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.64.3.1004

Authors: Phillip Nelson, Winfred Ruffner, Marshall Nirenberg

Institution: National Institutes of Health

Language: English

Topic: Ion channel regulation and function

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2005707569

FWCI: 4.026

Cites: 10

Cited by: 170

Related to: 10