The prevalence of subclinical hypercorticism among the patients presenting with type 2 diabetes mellitus and alimentary obesity
Year: 2014
Type: article
Study design: Observational Study
Abstract: Subclinical hypercorticism is characterized by increased cortisol secretion in the absence of the specific clinical manifestations of the disease. The prevalence of subclinical hypercorticism has been estimated at 8 cases per 10,000 population even though the frequency of subclinical hypercorticism may be higher among certain groups of the patients. We observed 111 patients presenting with type 2 diabetes mellitus and 40 ones with alimentary obesity. As a result, subclinical hypercorticism was diagnosed in 4 (10%) patients with obesity and in 12 (12%) ones with diabetes mellitus. In two of these cases, the diagnosis was later changed to clinically manifested hypercorticism. The imaging studies revealed pathological changes in pituitary and adrenal glands in six of the 16 patients presenting with subclinical hypercorticism. An algorithm for the examination of the patients with type 2 diabetes mellitus and alimentary obesity for the purpose of diagnostics of subclinical hypercorticism is proposed.
Source: Problems of Endocrinology
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2006166353