Efficacy of Omeprazole Paste in the Prevention of Gastric Ulcers in 2 Years Old Thoroughbreds
Year: 2012
Type: article
Abstract: Prevalence of equine gastric ulcer syndrome in 85 young Thoroughbreds was investigated. The presence of gastric ulcers was confirmed in 27.1% (23/85) of the horses by endoscopic examination. Sixty-two horses without gastric ulcers were allocated randomly to either the treated group (31 horses) or sham-dosed control group (31 horses) in order to investigate the efficacy of omeprazole oral paste in the prevention of gastric ulcers. At the second endoscopic examination conducted after 28 days of administration, only 1 horse in the treated group developed gastric ulcers, while 12 horses developed gastric ulcers in the control group. Based on these data, the efficacy of omeprazole in prevention of equine gastric ulcers in young Thoroughbreds during the training period was confirmed.
DOI: 10.1292/jvms.11-0545
Authors: Yoshiro ENDO, Takeru TSUCHIYA, Fumio SATO, Harutaka MURASE, Takaya OMURA, Kenji KOROSUE, Yasuo NAMBO, Mutsuki ISHIMARU, Yasuhiro WAKUI
Institutions: Japan Racing Association, Gifu University
Language: English
Subfield: Equine
Field: Veterinary
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W2007653270