Work

In Vitro Activities of Tigecycline against Erythromycin-Resistant Streptococcus pyogenes and Streptococcus agalactiae : Mechanisms of Macrolide and Tetracycline Resistance

Year: 2003

Type: article

Abstract: The activity of tigecycline was tested against erythromycin-resistant streptococci (107 Streptococcus pyogenes and 98 Streptococcus agalactiae strains). The presence of erythromycin and tetracycline resistance genes was determined by PCR. Among S. pyogenes strains the most prevalent gene was mef(A) (91.6%). The erm(B) gene was the most prevalent (65.3%) among S. agalactiae strains. Tigecycline proved to be very active against all the isolates tested (MIC at which 90% of the isolates tested were inhibited, 0.06 micro g/ml), including those resistant to tetracycline.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.48.1.323-325.2004

Authors: C. Betriu, E. Culebras, I. Rodríguez-Avial, M. Gómez, B. A. Sánchez, J. J. Picazo

Institution: Hospital Clínico San Carlos

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Microbiology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2008228367

FWCI: 4.437

Cites: 22

Cited by: 56

Related to: 10