Work

Lab-on-a-chip devices: How to close and plug the lab?

Year: 2014

Type: article

Abstract: Lab-on-a-chip (LOC) devices are broadly used for research in the life sciences and diagnostics and represent a very fast moving field. LOC devices are designed, prototyped and assembled using numerous strategies and materials but some fundamental trends are that these devices typically need to be (1) sealed, (2) supplied with liquids, reagents and samples, and (3) often interconnected with electrical or microelectronic components. In general, closing and connecting to the outside world these miniature labs remain a challenge irrespectively of the type of application pursued. Here, we review methods for sealing and connecting LOC devices using standard approaches as well as recent state-of-the-art methods. This review provides easy-to-understand examples and targets the microtechnology/engineering community as well as researchers in the life sciences.

Source: Microelectronic Engineering

DOI: 10.1016/j.mee.2014.10.013

Authors: Yuksel Temiz, Robert D. Lovchik, Govind V. Kaigala, Emmanuel Delamarche

Institution: IBM Research - Zurich

Language: English

Topic: Microfluidic and Capillary Electrophoresis Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $2,860

Funder: European Commission