A New Actinomycin Complex Produced by a Micromonospora Species: Fermentation, Isolation, and Characterization
Year: 1976
Type: article
Abstract: A species of Micromonospora, Micromonospora floridensis NRRL 8020, has been found to produce an actinomycin complex consisting of at least 25 active components. After solvent extraction of the complex, separation of the individual components was carried out by preparative thin-layer chromatography. Hydrolysis and subsequent electrophoretic and chromatographic identification of the amino acid content of each of the isolated components have shown differences from known actinomycins, and the probability exists that these contain a number of amino or imino acids not previously found in other members of this group of antibiotics.
DOI: 10.1128/aac.9.3.465
Authors: G. H Wagman, J. A. Marquez, P. D. Watkins, F. Gentile, A. Murawski, M. Patel, M. J. Weinstein
Language: English
Subfield: Applied Microbiology and Biotechnology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
Funder: Georgetown University
OpenAlex ID: W2010718263