Pathology of the Testicle and Sex Accessory Glands Following the Administration of Boldenone and Boldione as Growth Promoters in Veal Calves
Year: 2007
Type: article
Abstract: Boldenone and its precursor Boldione are illegally used for anabolic purposes in humans, horses and cattle. To develop more effective policies and programs to maximize food security, Italian Public Health Services investigate all indicators capable of assisting the recognition of treated animals, and prioritize research and the formulation of action strategies for the promotion of healthy eating. Thus, an experimental administration of boldenone and boldione at anabolic dosages in veal calves was carried out to evaluate the changes in target organs by qualitative and semi-quantitative morphological analysis. The lesions resembled the effects already observed after the administration of androgen hormones to cattle. Main findings were represented by prostate hypersecretion, increased rate of apoptotic cells and decreased rate of Ki67 positive cells in the germ cell line of treated animals, particularly in boldione group and finally some new features like hypertrophy of the prostate urothelial cells.
DOI: 10.1292/jvms.69.1109
Authors: Francesca T. CANNIZZO, Gabriele ZANCANARO, Francesca SPADA, Chiara MULASSO, Bartolomeo BIOLATTI
Institutions: University of Turin, Regione Piemonte
Language: English
Subfield: Animal Science and Zoology
Domain: Life Sciences
Open Access status: hybrid
Funder: Regione Piemonte
OpenAlex ID: W2012157745
