Work

Viral Load and Integration Status of High-Risk Human Papillomaviruses in the Barrett's Metaplasia–dysplasia–adenocarcinoma Sequence

Year: 2013

Type: article

Abstract: Recently, we demonstrated a strong association of transcriptionally active high-risk human papillomavirus (hr-HPV) with Barrett s dysplasia (BD) and esophageal adenocarcinoma (EAC) (1). To further clarify the role of hr-HPV infection in the Barrett s metaplasia dysplasia adenocarcinoma sequence, esophageal specimens positive for hr-HPV-16 or hr-HPV-18 DNA obtained from 83 patients (mostly recruited from our previous study) (1) were utilized to assess viral load and integration status.

Source: The American Journal of Gastroenterology

DOI: 10.1038/ajg.2013.206

Authors: Bin Wang, Shanmugarajah Rajendra, Darren Pavey, Prateek Sharma, Neil Merrett, Xiaojuan Wu, Elizabeth T Snow, Vivek Kumbhari, Madeleine J Ball, Iain K Robertson

Institutions: UNSW Sydney, Ingham Institute, Bankstown Lidcombe Hospital, South Western Sydney Local Health District, Kansas City VA Medical Center, Western Sydney University, University of Tasmania

Language: English

Topic: Esophageal Cancer Research and Treatment

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2012257804

FWCI: 2.231

Cites: 5

Cited by: 30

Related to: 10