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Palladium–copper-cocatalyzed intramolecular oxidative coupling: an efficient and atom-economical strategy for the synthesis of 3-acylindoles

Year: 2013

Type: article

Abstract: A new and efficient catalytic approach to the synthesis of 3-acylindoles under Pd-Cu-cocatalyzed oxidative conditions is demonstrated. tert-Butyl hydroperoxide (TBHP) acts not only as the oxidant, but also as an oxygen source in the approach. The process allows quick and atom-economical assembly of 3-acylindoles from readily available starting materials and tolerates a broad range of functional groups.

Source: Chemical Communications

DOI: 10.1039/c2cc37805a

Authors: Xiao-Feng Xia, Lu-Lu Zhang, Xian-Rong Song, Yan-Ning Niu, Xue-Yuan Liu, Yong-Min Liang

Institutions: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Chinese Academy of Sciences, Lanzhou Institute of Chemical Physics, State Key Laboratory of Solid Lubrication

Language: English

Topic: Catalytic Cross-Coupling Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W2012258134

FWCI: 5.435

Cites: 55

Cited by: 61

Related to: 10