Work

Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid‑β Aggregation and To Exert Anticholinesterase and Antioxidant Effects

Year: 2014

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/jm5010804

Authors: Eugenie Nepovimova, Elisa Uliassi, Jan Korabecny, Luis Emiliano Peña-Altamira, Sarah Samez, Alessandro Pesaresi, Gregory E. Garcia, Manuela Bartolini, Vincenza Andrisano, Christian Bergamini, Romana Fato, Doriano Lamba, Marinella Roberti, Kamil Kuca, Barbara Monti, Maria Laura Bolognesi

Institutions: Charles University, University Hospital Hradec Králové, University of Bologna, University of Defence, University of Trieste, AREA Science Park, National Research Council, United States Army

Language: English

Topic: Cholinesterase and Neurodegenerative Diseases

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Univerzita Hradec Králové, Fakultní nemocnice Hradec Králové, Grantová Agentura České Republiky

Awards: G2273660002, Novel inhibitors of acetylcholinesterase derived from 7-MEOTA - potential Alzheimer´s disease drugs

OpenAlex ID: W2013176372

FWCI: 16.72

Cites: 75

Cited by: 154

Related to: 10