Work

Impact of heart magnetic resonance imaging on chelation choices, compliance with treatment and risk of heart disease in patients with thalassaemia major

Year: 2013

Type: article

Abstract: This study aimed to verify the impact of heart magnetic resonance imaging on chelation choices and patient compliance in a single-institution cohort as well as its predictive value for heart failure and arrhythmias. Abnormal cardiac T2* values determined changes in treatment in most subjects. Heart T2* was confirmed to be highly predictive over 1 year for heart failure and arrhythmias. The choice of chelation regimens known to remove heart iron efficiently was not sufficient by itself to influence the risk. Compliance with treatment had a more remarkable role.

Source: British Journal of Haematology

DOI: 10.1111/bjh.12517

Authors: Raffaella Origa, Fabrice Danjou, Stefano Cossa, Gildo Matta, Patrizio Bina, Carlo Dessì, Elisabetta Defraia, Maria L. Foschini, GiovanBattista Leoni, Maddalena Morittu, Renzo Galanello

Institutions: Ospedale Microcitemico, Azienda Ospedaliero-Universitaria Cagliari, Azienda Ospedaliera G. Brotzu

Language: English

Topic: Hemoglobinopathies and Related Disorders

Subfield: Genetics (clinical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2014067158

FWCI: 1.419

Cites: 7

Cited by: 37

Related to: 10