A Case of Growth Hormone Deficiency with IgA Nephropathy and Insulin Dependent Diabetes Mellitus (IDDM)
Year: 1998
Type: article
Study design: Case Report
Abstract: A nine-year-old girl was first found to have microscopic hematuria and proteinuria when she was diagnosed with growth hormone deficiency. As the results of urinalysis had not changed for three months, growth hormone treatment was started. At the age of nine-years and eight-months, a kidney biopsy was performed because the hematuria had gradually increased. The pathologic diagnosis was IgA nephropathy group I. After 2.5 years of GH treatment, glycosuria developed. She was diagnosed with IDDM and the GH treatment was discontinued. The second renal biopsy showed IgA nephropathy group II. She was treated with azathioprine for two years. The microhematuria and proteinuria decreased. Currently at 15.6 years of age, her height is 148 cm (-3.1 SD) and IDDM has been well controlled.
Source: Clinical Pediatric Endocrinology
DOI: 10.1297/cpe.7.59
Institution: Hakodate Goryoukaku Hospital
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2016137971