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Neuronal Intranuclear Inclusion Disease Presenting with Resting Tremor

Year: 2014

Type: article

Abstract: Neuronal intranuclear inclusion disease (NIID) is a rare neurodegenerative disease with various neurological symptoms. A 73-year-old woman presented with slowly progressive tremor in both hands. The resting tremor was enhanced by cognitive activity and walking. However, there were no other signs of parkinsonism. Levodopa and trihexyphenidyl were ineffective against the tremor. A diagnosis of NIID was made based on skin biopsy findings. The tremor in this case was very similar to that seen in Parkinson's disease (PD). Previous reports and the present case indicate that NIID patients can develop tremor that is similar in character to that seen in PD. NIID should be considered in the differential diagnosis of resting tremor similar to PD.

Source: Case Reports in Neurology

DOI: 10.1159/000363687

Authors: Naoyuki Kitagawa, Jun Sone, Gen Sobue, Masahiko Kuroda, Michio Sakurai

Institutions: Tokyo Medical University, Kohsei Chuo General Hospital, Nagoya University

Language: English

Topic: Genetic Neurodegenerative Diseases

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,030