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Synthetic Farnesoid X Receptor Agonists Induce High-Density Lipoprotein-Mediated Transhepatic Cholesterol Efflux in Mice and Monkeys and Prevent Atherosclerosis in Cholesteryl Ester Transfer Protein Transgenic Low-Density Lipoprotein Receptor (−/−) Mice

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Year: 2012
Type: article
Source: Journal of Pharmacology and Experimental Therapeutics
DOI: 10.1124/jpet.112.196519
Authors: Eva Hambruch, Shinobu Miyazaki-Anzai, Ulrike Hahn, Silke Matysik, Alfred Boettcher, Sanja Perović-Ottstadt, Thomas Schlüter, Olaf Kinzel, Helen Desiree Krol, Ulrich Deuschle, Michael Burnet, Moshe Levi, Gerd Schmitz, Makoto Miyazaki, Claus Kremoser
Institutions: University Hospital Regensburg, Phenex Pharmaceuticals (Germany), Synovo (Germany), University of Colorado Denver, University of Regensburg
Language: English

Topic: Cholesterol and Lipid Metabolism
Subfield: Biochemistry
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Veterans Affairs, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: Treatment of Kidney Disease in Diabetes and Obesity, G8034811188, Colorado Nutrition Obesity Research Center
OpenAlex ID: W2017257127
FWCI: 3.806
Cites: 71
Cited by: 100
Related to: 10
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