Work

Antibacterial activity of copper-containing clinoptilolite/PVC composites toward clinical isolate of Acinetobacter baumannii

Year: 2015

Type: article

Abstract: The multidrug resistant bacteria Acinetobacter baumannii cause serious hospital infections. Commercial poly(vinyl chloride) (PVC) used for endotracheal tubes was modified in order to obtain the composite with antibacterial effect towards clinical isolate of A. baumannii ST145. The composites were prepared by addition of different amounts of copper-containing zeolite tuff (CuZ) and by successive impregnation with D-Tyrosine (D-Tyr) solution. The composites which were obtained by addition of CuZ (CuZ-PVC) only did not exhibit antibacterial effect. The impregnation of the CuZ-PVC by D-Tyr resulted in an antibacterial effect which is explained by a synergistic effect of CuZ and D-Tyr. Rheological tests confirmed that the modification of PVC by CuZ does not affect its processability and reformability.

Source: Journal of the Serbian Chemical Society

DOI: 10.2298/jsc141225017m

Authors: Jelena Milenkovic, Jasna Hrenovic, Ivana Goic-Barisic, Milos Tomic, Nevenka Rajic

Institutions: University of Belgrade, University of Zagreb, Klinički Bolnički Centar Split, University of Split

Language: English

Topic: Antimicrobial agents and applications

Subfield: Applied Microbiology and Biotechnology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Sveučilište u Zagrebu, Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja