Year: 2011
Type: article
Study design: Case Report
Abstract: A30-year-old man, with no prior pathologic antecedent was admitted to the internal medicine department for a 3 month history of cough and bloody sputum.These symptoms occurred in the context of apyrexia, night sweating and 6 kilogram weight loss.On physical examination the patient appeared pale, BMI was 17 kg/m 2 , crackles were heard in the left lung.The skin examination noted painful genital and oral ulcers with pustlar lesions in the back.Chest X-ray showed left hilar opacity.Angio CT scan revealed an aneurysm of the left inferior pulmonary artery (Picture 1) with parietal thrombus, right basal pulmonary infarction, and right intra-atrial thrombus (Picture 2).Echocardiography noted the mobile thrombus in the right atrium (Picture 3) and another thrombus in the vena cava junction.Laboratory tests found inflammatory anemia.The infectious analysis (VDRL-TPHA, Mycobacteria) was negative.There were definite findings for thrombophilia or connectivitis, however HLA-B51 was positive.The diagnosis of Behçet's disease was made.The patient was treated with cyclophosphamide and methylprednisolone pulses relayed by oral prednisone 1 mg/kg/j and anticoagulation.After 5 months there was disappearance of intracardiac thrombi and marked regression of the pulmonary artery aneurysm.The location is rare in Behçet's disease: from 1 to 5% in clinical series, 16.5% on a register of autopsies in Japan and
Source: Internal Medicine
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2017502438