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The Amino-Terminal Region of Major Capsid Protein P3 Is Essential for Self-Assembly of Single-Shelled Core-Like Particles of Rice Dwarf Virus

Year: 2004
Type: article
Abstract: The core protein P3 of Rice dwarf virus constructs asymmetric dimers, one of which is inserted by the amino-terminal region of another P3 protein. The P3 proteins with serial amino-terminal deletions, expressed in a baculovirus system, formed particles with gradually decreasing stability. The capacity for self-assembly disappeared when 52 of the amino-terminal amino acids had been deleted. These results demonstrated that insertion of the amino-terminal arm of one P3 protein into another appears to play an important role in stabilizing the core particles.
DOI: 10.1128/jvi.78.6.3145-3148.2004
Authors: Kyoji Hagiwara, Takahiko Higashi, Naoyuki Miyazaki, Hisashi Naitow, R. Holland Cheng, Atsushi Nakagawa, Hiroshi Mizuno, Tomitake Tsukihara, Toshihiro Omura
Institutions: National Agriculture and Food Research Organization, Institute for Protein Research, The University of Osaka, The University of Osaka, RIKEN, Karolinska Institutet, Institute of Agrobiological Sciences
Language: English
Subfield: Plant Science
Open Access status: green
OpenAlex ID: W2018291935
FWCI: 1.238
Cites: 9
Cited by: 21
Related to: 10