Work

Quantification of neurotoxin BMAA (β-N-methylamino-L-alanine) in seafood from Swedish markets

Year: 2014

Type: article

Abstract: The neurotoxin β-N-methylamino-L-alanine (BMAA) produced naturally by cyanobacteria, diatoms and dinoflagellates can be transferred and accumulated up the food chain, and may be a risk factor for neurodegenerative diseases. This study provides the first systematic screening of BMAA exposure of a large population through the consumption of seafood sold in metropolitan markets. BMAA was distinguished from known isomers by liquid chromatography tandem mass spectrometry after acidic hydrolysis and derivatization. Using deuterium-labeled internal standard, BMAA was quantified as 0.01-0.90 μg/g wet weight of tissues in blue mussel, oyster, shrimp, plaice, char and herring, but was undetectable (<0.01 μg/g) in other samples (salmon, cod, perch and crayfish). Provided that the content of BMAA detected is relevant for intake calculations, the data presented may be used for a first estimation of BMAA exposure through seafood from Swedish markets, and to refine the design of future toxicological experiments and assessments.

Source: Scientific Reports

DOI: 10.1038/srep06931

Authors: Liying Jiang, Nadezda Kiselova, Johan Rosén, Leopold L. Ilag

Institutions: Stockholm University, National Food Administration

Language: English

Topic: Marine Toxins and Detection Methods

Subfield: Environmental Chemistry

Field: Environmental Science

Domain: Physical Sciences

SDGs: Life below water, Good health and well-being

Open Access status: gold

Estimated APC paid: $2,690