Work

Rheumatoid arthritis is associated with increased DKK1 expression and disturbances in the bone turnover regulating genes

Year: 2011

Type: article

Study design: Observational Study

Abstract: Materials and methods RA patients submitted to hip replacement surgery were recruited. They were matched to a group of primary OP patients for bone mineral density and major clinical fracture risk factors (age, gender, BMI). Trabecular bone microarchitecture was assessed by micro-computed tomography and bone mechanical behavior by compression tests. Bone cell activity was analyzed by studying gene expression.

Source: Journal of Translational Medicine

DOI: 10.1186/1479-5876-9-s2-p53

Authors: Joana Caetano-Lopes, Ana Rodrigues, Ana Lopes, Ana C Vale, Michael A Pitts-Kiefer, Bruno Vidal, Inês P Perpétuo, Jacinto Monteiro, Yrjö T Konttinen, Maria F Vaz, Ara Nazarian, Helena Canhão, João E Fonseca

Institutions: University of Lisbon, Instituto de Medicina Molecular João Lobo Antunes, Hospital de Santa Maria, Instituto Superior Técnico, Beth Israel Deaconess Medical Center, Harvard University, University of Helsinki, Coxa Hospital, Tekonivelsairaala Orton

Language: English

Topic: Bone health and osteoporosis research

Subfield: Orthopedics and Sports Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,890

OpenAlex ID: W2018936859

FWCI:

Cites:

Cited by: 1

Related to: 10