Secondary Hemophagocytic Lymphohistiocytosis in Turkish Children
Year: 2005
Type: article
Study design: Observational Study
Abstract: Between January 1998 and January 2005, a total of 18 children 2 weeks-72 months of age were diagnosed as having secondary hemophagocytic lymphohistiocytosis. The frequency of secondary hemophagocytic lymphohistiocytosis among total hospitalized patients during this period was 0.05% (18 of 34,250). Of the 18 patients, 8 (44.5%) had bacterial infections; cytomegalovirus and Epstein-Barr virus infections were present in 5 (28%) and 1 (5.5%), patient, respectively. Leishmaniasis was diagnosed in 2 patients (11%), and herpes simplex virus was diagnosed in 2 patients (11%). Six patients died during treatment, and 1 patient was lost to follow-up. The survival rate was 61%.
Authors: Aytemiz Gurgey, Gulten Secmeer, Betul Tavil, Mehmet Ceyhan, Baris Kuskonmaz, Bulent Cengiz, Hasan Ozen, Ates Kara, Mualla Cetin, Fatma Gumruk
Institution: Hacettepe University
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2020439301