Work

Comparative in vitro activities of pristinamycin, its components, and other antimicrobial agents against anaerobic bacteria

Year: 1988

Type: article

Abstract: Using an agar dilution technique, we compared the activities of pristinamycin and its components PIA and PIIA with those of penicillin G, cefoxitin, chloramphenicol, metronidazole, and clindamycin against 200 strains of anaerobic bacteria isolated from suppurative lesions. The antimicrobial activity of pristinamycin was similar to that of chloramphenicol. On the basis of these results and because of its antistaphylococcal and antistreptococcal activities and its absence of toxicity, pristinamycin might be a valuable therapeutic agent for treating mixed aerobic-anaerobic cutaneous infections.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.32.7.1094

Authors: H Laforest, M Fourgeaud, H Richet, P H Lagrange

Institution: Hôtel-Dieu de Paris

Language: English

Topic: Antibiotics Pharmacokinetics and Efficacy

Subfield: Pharmacology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2020797482

FWCI: 1.21

Cites: 6

Cited by: 9

Related to: 10