Work

In Vitro Activity of 39 Antimicrobial Agents Against Treponema hyodysenteriae

Year: 1979

Type: article

Abstract: The in vitro activities of 39 antimicrobial agents against 23 isolates of Treponema hyodysenteriae, the majority of which were field isolates, were determined by the agar dilution technique. Quinoxalines, pleuromutilin, nitroimidazoles, and nitrofuran were the most active. Their activities ranged from </=0.10 to 1.56 mug/ml. Lincomycin, penicillins, chloramphenicol, tetracyclines, cephalosporins, three peptides (virginiamycin, thiopeptin, and bacitracin), and one aminoglycoside (gentamicin) exhibited intermediate levels of activity ranging from 0.39 to 50 mug/ml. Four peptides (enduracidin, viomycin, bicyclomycin, and colistin), three aminoglycosides (kanamycin, streptomycin, and neomycin), polyene, and other agents, including novobiocin, vancomycin, rifampin, nalidixic acid, and p-arsanilic acid, displayed limited activities ranging from 12.5 to >/=100 mug/ml. Macrolides showed varying degrees of activity depending upon isolates.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.15.3.392

Authors: Kazuhisa Kitai, Mamoru Kashiwazaki, Yoshikazu Adachi, Tsuneo Kume, Akira Arakawa

Institution: National Institute of Animal Health

Language: English

Topic: Veterinary medicine and infectious diseases

Subfield: Small Animals

Field: Veterinary

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2020887499

FWCI: 1.262

Cites: 22

Cited by: 31

Related to: 10