Work

Immunoglobulin G heavy chain (Gm) allotypes in multiple sclerosis.

Year: 1981

Type: article

Abstract: Serum samples from 70 Caucasian patients with multiple sclerosis were typed for nine Gm markers. Significant association was found with the Gm 1,17;21 phenotype, and the relative risk for individuals with this phenotype was calculated at 3.6. The data indicate that Caucasians positive for Gm 1,17;21 are almost four times more likely to develop multiple sclerosis than those without this phenotype.

Source: Journal of Clinical Investigation

DOI: 10.1172/jci110220

Authors: J P Pandey, J M Goust, J P Salier, H H Fudenberg

Institution: Medical University of South Carolina

Language: English

Topic: Multiple Sclerosis Research Studies

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: University of South Carolina, Multiple Sclerosis Society