Work

Development of Eosinophilia in dogs intradermically inoculated with sand fly saliva and Leishmania (Leishmania) chagasi stationary-phase promastigotes

Year: 1993

Type: article

Abstract: Salivary gland lysates of the sand fly Lutzomia longipalpis have been shown to enhance the infectivity of Leishmania in mice. As shown herein, the simultaneous inoculation of Leishmania chagasi stationary-phase promastigotes and L. longipalpis salivary gland lysate by the intradermal route in a group of mongrel dogs induced a statistically significant eosinophilia, in relation to dogs inoculated with Leishmania or with salivary gland lysate only. These dogs had no evidence of infection, in spite of the high infectivity of the promastigotes when inoculated by the intravenous route.

Source: Memórias do Instituto Oswaldo Cruz

DOI: 10.1590/s0074-02761993000200012

Authors: Moacir Paranhos, Washington C. dos Santos, Italo Sherlock, Geraldo G. S. Oliveira, Lain C. Pontes de Carvalho

Institution: Fundação Oswaldo Cruz

Language: English

Topic: Research on Leishmaniasis Studies

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2022947749

FWCI:

Cites:

Cited by: 24

Related to: 10