Work

Synthesis of Allyl Ester of Prostaglandin E and the Conversion of the Allyl Ester Moiety into Carboxylic Acid by Chemical Method. A Highly Practical Synthesis of Natural PGE1 and Limaprost

Year: 1992

Type: article

Abstract: Synthesis of prostaglandin E allyl ester via two-component coupling process and the conversion of the allyl ester moiety into free carboxylic acid by the reaction with HCO2H-Et3N in the presence of a palladium catalyst has been described.

Source: Chemistry Letters

DOI: 10.1246/cl.1992.2095

Authors: Naoya Ono, Mie Tsuboi, Sentaro Okamoto, Tohru Tanami, Fumie Sato

Institutions: Tokyo Institute of Technology, Taisho Pharmaceutical (Japan)

Language: English

Topic: Catalytic Cross-Coupling Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W2024646348

FWCI: 0.639

Cites: 13

Cited by: 4

Related to: 10