Discovery of a Biaryl Cyclohexene Carboxylic Acid (MK-6892): A Potent and Selective High Affinity Niacin Receptor Full Agonist with Reduced Flushing Profiles in Animals as a Preclinical Candidate
Year: 2010
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/jm100022r
Authors: Hong C. Shen, Fa-Xiang Ding, Subharekha Raghavan, Qiaolin Deng, Silvi Luell, Michael J. Forrest, Ester Carballo-Jane, Larissa C. Wilsie, Mihajlo L. Krsmanovic, Andrew K. Taggart, Kenneth K. Wu, Tsuei-Ju Wu, Kang Cheng, Ning Ren, Tian-Quan Cai, Qing Chen, Junying Wang, Michael S. Wolff, Xinchun Tong, Tom G. Holt, M. Gerard Waters, Milton L. Hammond, James R. Tata, Steven L. Colletti
Institution: Merck & Co., Inc., Rahway, NJ, USA (United States)
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: closed
OpenAlex ID: W2024929585