Work

Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide

Year: 2014

Type: article

Abstract: Here we describe the use of a new open-source software package and a Raspberry Pi(®) computer for the simultaneous control of multiple flow chemistry devices and its application to a machine-assisted, multi-step flow preparation of pyrazine-2-carboxamide - a component of Rifater(®), used in the treatment of tuberculosis - and its reduced derivative piperazine-2-carboxamide.

Source: Beilstein Journal of Organic Chemistry

DOI: 10.3762/bjoc.10.56

Authors: Richard J Ingham, Claudio Battilocchio, Joel M Hawkins, Steven V Ley

Institutions: University of Cambridge, Pfizer (United States)

Language: English

Topic: Innovative Microfluidic and Catalytic Techniques Innovation

Subfield: Fluid Flow and Transfer Processes

Field: Chemical Engineering

Domain: Physical Sciences

Open Access status: diamond

Funder: Pfizer

OpenAlex ID: W2039754759