Discovery of Checkpoint Kinase Inhibitor (S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide (AZD7762) by Structure-Based Design and Optimization of Thiophenecarboxamide Ureas
Year: 2012
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/jm300025r
Authors: Vibha Oza, Susan Ashwell, Lynsie Almeida, Patrick Brassil, Jason Breed, Chun Deng, Thomas Gero, Michael Grondine, Candice Horn, Stephanos Ioannidis, Dongfang Liu, Paul Lyne, Nicholas Newcombe, Martin Pass, Jon Read, Shannon Ready, Siân Rowsell, Mei Su, Dorin Toader, Melissa Vasbinder, Dingwei Yu, Yan Yu, Yafeng Xue, Sonya Zabludoff, James Janetka
Language: English
Subfield: Drug Discovery
Domain: Life Sciences
Open Access status: closed
OpenAlex ID: W2043749332