Real-time proton beam range monitoring by means of prompt-gamma detection with a collimated camera
Year: 2014
Type: article
Abstract: Prompt-gamma profile was measured at WPE-Essen using 160 MeV protons impinging a movable PMMA target. A single collimated detector was used with time-of-flight (TOF) to reduce the background due to neutrons. The target entrance rise and the Bragg peak falloff retrieval precision was determined as a function of incident proton number by a fitting procedure using independent data sets. Assuming improved sensitivity of this camera design by using a greater number of detectors, retrieval precisions of 1 to 2 mm (rms) are expected for a clinical pencil beam. TOF improves the contrast-to-noise ratio and the performance of the method significantly.
Source: Physics in Medicine and Biology
Institutions: Lyon 1 Université, Centre National de la Recherche Scientifique, Université de Lyon, Ion Beam Applications (Belgium), Centre Léon Bérard, Institut National de Physique Nucléaire et de Physique des Particules, Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé, Institute of Nuclear Physics of Lyon, Institut de Physique des 2 Infinis de Lyon, Institut National des Sciences Appliquées de Lyon
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2043937464