One‐Pot and Convenient Conversion of 5‐Azidopyrazole‐4‐carboxaldehyde to Pyrazolo[3,4‐b]pyridines
Year: 2006
Type: article
Abstract: A one‐pot and convenient synthesis of multisubstituted pyrazolo[3,4‐b]pyridines in moderate to high yields has been achieved by a two‐step reaction: diazo‐transfer of 5‐azido‐1‐phenylpyrazole‐4‐carboxaldehydes to ketones in ethanolic KOH to give 5‐amino‐1‐phenylpyrazole‐4‐carboxaldehyde and subsequent Friedlaender reaction of 5‐amino‐1‐phenylpyrazole‐4‐carboxaldehyde with ketones.
Source: Synthetic Communications
Authors: Airong Zheng, Wei Zhang, Jinhui Pan
Institution: Lanzhou University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W2048486013