Work

Reflection-type long period grating biosensor for the detection of drug resistant bacteria: The Opto-bacteria Project

Year: 2014

Type: conference-paper

Abstract: We report on the development of a multilayer coated reflection-type long period fiber grating (LPG) biosensor, useful for the detection of antibiotic resistance bacteria. A standard LPG is first transformed in a more practical probe working in reflection mode, then it is coated by a primary layer of aPS and a secondary layer of PMMA in order to increase its surrounding refractive index sensitivity and at the same time provide the necessary conditions for a correct biofunctionalization. Standard linkage chemistry has been applied to anchor the bioreceptors on the probe surface. We show some preliminary results demonstrating the capability of our LPG biosensor to successfully monitor all the biological steps of the biomolecular experiments, including β-lactamase binding detection tests.

Source: Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE

DOI: 10.1117/12.2059783

Authors: M. Consales, G. Quero, S. Zuppolini, L. Sansone, A. Borriello, M. Giordano, A. Venturelli, A. Cusano

Institutions: University of Sannio, National Research Council, Tydock Pharma (Italy)

Language: English

Topic: Advanced Fiber Optic Sensors

Subfield: Electrical and Electronic Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W2048627489

FWCI: 0.802

Cites: 11

Cited by: 5

Related to: 10