Work

Three Translocations Involving C- or G-group Chromosomes

Year: 1973

Type: article

Abstract: Three translocations each involving C or G chromosomes are reported. A familial translocation t(Cq+; Eq−) was identified to be rcp(6;18) (q2;q1) and two malformed children were then found to have a 46,XY(or XX),−6, +der(6) constitution. One of the carrier's pregnancy in this family was monitored by amniocentesis and a fetus was identified as being a male translocation carrier (balanced). Two other translocations were identified as rcp(11;14) (q12 or 13;q32?) and t(17;22) (p12 or 13?;q11?), respectively.

Source: Journal of Medical Genetics

DOI: 10.1136/jmg.10.2.174

Authors: Yasuo Nakagome, Kazuso Iinuma, Ichiro Matsui

Institutions: National Institute of Genetics, Wayne State University, Kanagawa Children's Medical Center, Children's Hospital of Michigan

Language: English

Topic: Genomic variations and chromosomal abnormalities

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2048758913