Work

Nucleophilic substitution at the halogen atom (halogenophilic reactions)

Year: 2012

Type: article

Abstract: The key features of halogenophilic reactions defining their role in organic chemistry are considered. The results of studies of mechanisms involving a nucleophilic attack at the halogen atom (SN2Hal) are summarized. The main mechanistic evidence comes from the studies of halogen–metal exchange reactions. Primary attention is paid to the role of halogenophilic reaction as a competing process or a concealed mechanism in ordinary nucleophilic substitution reaction at carbon atoms. The bibliography includes 249 references.

Source: Russian Chemical Reviews

DOI: 10.1070/rc2012v081n04abeh004216

Authors: Petr K Sazonov, Galina A Artamkina, Irina P Beletskaya

Institution: Lomonosov Moscow State University

Language: English

Topic: Physical Organic Chemistry and Reaction Kinetics

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

OpenAlex ID: W2054925552

FWCI: 1.913

Cites: 169

Cited by: 55

Related to: 10