Work

Juvenile dermatomyositis: A review of clinical features and management

Year: 2012

Type: article

Abstract: Juvenile dermatomyositis is the most common of the idiopathic inflammatory myositis of childhood. It is characterised by a pathognomic skin rash along with proximal muscle weakness. It may also affect organs other than the muscle and skin. Calcinosis and lipodystrophy are complications of long-standing untreated or poorly treated disease, associated with chronic morbidity. A variety of environmental and genetic risk factors are implicated in its pathogenesis. Up-regulation of genes by type-I interferon appears central. Corticosteroids along with methotrexate are the mainstay of therapy. Disease outcome is in general good.

Source: Indian Journal of Rheumatology

DOI: 10.1016/s0973-3698(12)60032-6

Authors: S Habibi, AV Ramanan

Institutions: Nizam's Institute of Medical Sciences, Royal National Hospital for Rheumatic Diseases, Bristol Royal Hospital for Children

Language: English

Topic: Inflammatory Myopathies and Dermatomyositis

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2055089451

FWCI: 0.2

Cites: 41

Cited by: 9

Related to: 10