Work

Compartmentalized regulation of macrophage arachidonic acid metabolism.

Year: 1986

Type: article

Abstract: We show that downregulation of arachidonic acid (20:4) metabolism which occurs following i.p. injection of C. parvum can occur in a single, localized macrophage population, and is therefore unlikely to be mediated solely by a systemic factor.

Source: The Journal of Experimental Medicine

DOI: 10.1084/jem.163.3.752

Authors: A O Fels, N A Pawlowski, E L Abraham, Z A Cohn

Institutions: Cornell University, Rockefeller University

Language: English

Topic: Inflammatory mediators and NSAID effects

Subfield: Pharmacology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Allergy and Infectious Diseases