Genomic Exploration of the Hemiascomycetous Yeasts: 20. Evolution of gene redundancy compared to Saccharomyces cerevisiae
Year: 2000
Type: article
Abstract: We have evaluated the degree of gene redundancy in the nuclear genomes of 13 hemiascomycetous yeast species. Saccharomyces cerevisiae singletons and gene families appear generally conserved in these species as singletons and families of similar size, respectively. Variations of the number of homologues with respect to that expected affect from 7 to less than 24% of each genome. Since S. cerevisiae homologues represent the majority of the genes identified in the genomes studied, the overall degree of gene redundancy seems conserved across all species. This is best explained by a dynamic equilibrium resulting from numerous events of gene duplication and deletion rather than by a massive duplication event occurring in some lineages and not in others.
Source: FEBS Letters
Authors: Bertrand Llorente, Pascal Durrens, Alain Malpertuy, Michel Aigle, François Artiguenave, Gaëlle Blandin, Monique Bolotin-Fukuhara, Elisabeth Bon, Philippe Brottier, Serge Casaregola, Bernard Dujon, Jacky de Montigny, Andrée Lépingle, Cécile Neuvéglise, Odile Ozier-Kalogeropoulos, Serge Potier, William Saurin, Fredj Tekaia, Claire Toffano-Nioche, Micheline Wésolowski-Louvel, Patrick Wincker, Jean Weissenbach, Jean-Luc Souciet, Claude Gaillardin
Institutions: Centre National de la Recherche Scientifique, Institut Pasteur, Department of Genomes & Genetics, Université Pierre-et-Marie-Curie, Institut de Biochimie et Génétique Cellulaires, Genoscope, Université Paris-Sud, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Institut National de la Recherche Agronomique, Lyon 1 Université, Institut National des Sciences Appliquées de Lyon
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
Funder: Institut Universitaire de France
OpenAlex ID: W2056433290