Work

Anti-bacterial and anti-fungal activity of coleus leaves consumed as breast-milk stimulant

Year: 2013
Type: article
Abstract: Purpose – The aim of this study was to evaluate anti-bacterial anti-fungal activity of six Lamiaceae family coleus plants based on their traditional uses (breast-milk stimulants) from two Asian countries (Malaysia and Indonesia). Design/methodology/approach – Plants leaves of coleus species were collected from Kuantan (Malaysia) and Jakarta (Indonesia). From Kuantan,Coleus aromaticus– Malaysia (CATM),Pogostemon cablin– Malaysia (PCM),Coleus blumei-purple leaves – Malaysia (CBPM),Coleus blumei-red leaves – Malaysia (CBRM),Coleus amboinicus– Malaysia (CALM) and from JakartaColeus amboinicus– Indonesia (CALI) were collected freeze dried and extracted with aqueous methanol. The antimicrobial activity of the extract was determined by making use of macro dilution and disc diffusion methods. The selected bacteria and fungus used were namelyBacillus subtilisandStaphylococcus aureus(gram positive) andEscherichia coliandPseudomonas aeruginosa(gram negative) andCandida albicans(a fungi). Findings – All leaf extracts showed activity at least against one strain of bacteria and the result shows that there were significant differences (p<0.05) between the activities on microorganism. The minimum inhibitory concentration of all leaves extracts ranged from 1.0 to 2.0 mg/ml in inhibiting the growth ofS. aureus,E. coli,P. aeruginosaandB. subtilis. This study shows that the coleus plants leaves can be used as anti-bacterial anti-fungal agent apart from the breast-milk stimulation properties. Research limitations/implications – This research was carried out with a limited grant and it was not possible to study some more aspects, for example, the composition and the active components isolation, etc. Furthermore, to establish the relationship among the components and bacteria or fungus, etc. Practical implications – This research would have greater impact since the leaves of coleus plants are already in use in some communities for the purpose of breast-milk stimulation and insect bite therapy and many more. Originality/value – This research takes into consideration the effect of coleus plants on a few bacteria and a fungus which have never been studied before.
Language: English
Subfield: Food Science
Open Access status: green
OpenAlex ID: W2056678313
FWCI: 1.114
Cites: 19
Cited by: 17
Related to: 10