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Severe Pancytopenia Induced by Low-dose Methotrexate in a Hemodialysis Patient

Year: 2010

Type: article

Abstract: Methotrexate has been used as an important alternative therapy in the treatment of various rheumatic diseases. It is primarily cleared by the kidney. Life-threatening marrow suppression in hemodialysis patients has been reported. A 35-year-old woman undergoing hemodialysis developed severe stomatitis and pancytopenia after low-dose methotrexate treatment for rheumatoid arthritis. She recovered after folinic acid, granulocyte colony-stimulating factor, antibiotic and daily hemodialysis therapy.

Source: Turkish Journal of Nephrology

DOI: 10.5262/tndt.2010.1002.75

Authors: Irem Pembegul Yigit, Ramazan Ulu, Yener Yildiz, Ayhan Dogukan, Huseyin Celiker

Language: English

Topic: Rheumatoid Arthritis Research and Therapies

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2058840403

FWCI:

Cites:

Cited by: 1

Related to: 10