Work

Synthesis of water soluble CdS nanoparticles and study of their DNA damage activity

Year: 2014

Type: article

Abstract: This study reports a novel method for preparation of water soluble CdS nanoparticles using leaf extract of a plant, Asparagus racemosus. The extract of the leaf tissue which worked as a stabilizing and capping agent, assisted the formation of nanoparticles. Nanoparticles were characterized using a UV–vis spectrophotometer, Photoluminescence, TEM, EDAX, XRD and FT-IR. Transmission electron microscopy followed by selected area electron diffraction pattern analysis indicated the formation of spherical, polydispersed, crystalline, CdS of diameter ranging from 2 to 8 nm. X-ray diffraction studies showed the formation of 1 1 1, 2 2 0 and 3 1 1 planes of face-centered cubic (fcc) CdS. EDAX analysis confirmed the presence of Cd and S in nanosphere. The cytotoxicity test using MTT assay as well as DNA damage analysis using comet assay revealed that synthesized nano CdS quantum dots (QDs) caused less DNA damage and cell death of lymphocytes than pure CdS nanoparticles.

Source: Arabian Journal of Chemistry

DOI: 10.1016/j.arabjc.2014.05.033

Authors: Kumar Suranjit Prasad, Tapan Amin, Saloni Katuva, Madhu Kumari, Kaliaperumal Selvaraj

Institutions: Maharaja Sayajirao University of Baroda, Babasaheb Bhimrao Ambedkar Bihar University, National Chemical Laboratory

Language: English

Topic: Nanoparticles: synthesis and applications

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $1,490

Funder: Department of Science and Technology, Ministry of Science and Technology, India