Measurement of red blood cell aggregation using X-ray phase contrast imaging
Year: 2010
Type: article
Abstract: When a coherent beam illuminates spatially disordered particles, speckle patterns are formed due to interference of the scattered light waves. Speckle patterns from biological tissues using synchrotron phase contrast X-ray imaging can provide functional information about micro-scale morphological structures of the tissues. In this study, we investigated the size and contrast variations of the speckles of aggregated red blood cells (RBCs) suspensions with varying the degree of RBC aggregation. Results show that the degree of RBC aggregation is a governing parameter on the change of speckle characteristics. This blood speckle analysis method can be used as a novel modality for monitoring RBC aggregation.
Source: Optics Express
DOI: 10.1364/oe.18.026052
Authors: Sang Joon Lee, Hojin Ha, Kweon-Ho Nam
Institution: Pohang University of Science and Technology
Language: English
Subfield: Radiation
Field: Physics and Astronomy
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,270
OpenAlex ID: W2063074705